Systematic review for the development of a core outcome set for monofocal intraocular lenses for cataract surgery

Author: Tarricone R, Rognoni  C, Ciarlo A, Giabbani I, Novello  L,  Balestrieri M, Costa G,  Favuzza E,  Mencucci R,  Taroni L, Tognetto D, Giglio R.

Geographical coverage:

Sector: Biomedical

Sub-sector: Treatment

Equity focus:  Not reported

Study population: Adult patients with cataracts

Review type: Effectiveness review

Quantitative synthesis method: The review used a mixed-methodology approach combining qualitative and quantitative techniques to develop a Core Outcome Set (COS) for monofocal intraocular lenses (IOLs) in cataract surgery.

Qualitative synthesis method: Mixed-methodology approach (as stated above)

Background:

Healthcare resource scarcity and supplier-induced demand can be managed by prioritising technologies that benefit all stakeholders, especially patients, by broadening clinical endpoint measurements beyond randomised controlled trials (RCTs) to include patient preferences. Core outcome sets (COS) are useful in fields with significant outcome variation or scarce data, and this work aims to advance COS in cataract research by incorporating real-world evidence and patient involvement, alongside RCTs, and specifying metrics for postoperative outcomes.

Objective:

To define a COS to be measured following cataract surgery for the postoperative evaluation of monofocal intraocular lenses (IOLs).

Main findings:

Methodology: