Summary

In June 2021, the World Health Organization (WHO), recognising the need for new diagnostics to support the control and elimination of onchocerciasis, published the target product profiles (TPPs) of new tests that would support the two most immediate needs: (a) mapping onchocerciasis in areas of low prevalence and (b) deciding when to stop mass drug administration programmes.

This article describes the methodology used to produce the TPPs, with an emphasis on calculating the required sensitivity and specificity characteristics.