Sightsavers Reports

Onchocerciasis: target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions

In June 2021, the World Health Organization (WHO), recognising the need for new diagnostics to support the control and elimination of onchocerciasis, published the target product profiles (TPPs) of new tests that would support the two most immediate needs: (a) mapping onchocerciasis in areas of low prevalence and (b) deciding when to stop mass drug administration programmes.

This article describes the methodology used to produce the TPPs, with an emphasis on calculating the required sensitivity and specificity characteristics.

Two male researchers screen a young child from Liberia for onchocerciasis by taking a blood sample.
Type
Original research
Theme
NTD
Date published
03/08/2022
Journal
PLOS Neglected Tropical Diseases
Language
English
Relevant links
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