Sightsavers Reports

Serological and PCR-based markers of ocular Chlamydia trachomatis transmission in northern Ghana after elimination of trachoma as a public health problem

Validation of elimination of trachoma as a public health problem is based on clinical indicators, which is increasingly problematic. Alternative indicators (antibody and infection) were integrated into the pre-validation trachoma surveys conducted in Ghana in 2015 and 2016.

This study shows that elimination of trachoma as a public health problem does not equate to the absence of ocular Chlamydia trachomatis (Ct) infection, nor cessation in acquisition of anti-Ct antibodies. Infection and serological data provide useful information to aid in understanding Ct transmission dynamics and identify communities at potential risk of recrudescence.

Type
Journal article
Theme
NTD
Date published
14/12/2018
Journal
PLOS Neglected Tropical Diseases
Language
English
Relevant links
Read the full study in PLOS NTD
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